Zandu Zandopa for Parkinson's disease

Zandu Zandopa for Parkinson's disease

Zandopa is a herbal remedy for the treatment of Parkinson's disease. The Zandopa 175gm product is a water soluble powder sourced from a plant called 'Mucuna pruriens' which contains a natural source of Levadopa. Zandopa is one of the first plant - based formulations to have received investigative approval from the United States Food and Drug Administration (FDA).

Zandopa Medicine is a unique product for parkinsonism

  • Zandopa has Better Tolerability.
  • Zandopa is a readily bioavailable natural source of L-Dopa (levodopa).
  • Zandopa is economical
  • Zandopa is suitable for longterm use.
In parkinson's disease Zandopa is a natural source of dopamine.

Benefits of Zandopa Medicine:

  • Zandopa, a unique research product, contains richest natural sources of L-dopa, the plasma half life of which is similar to that from synthetic L-dopa, carbidopa formulations; hence frequency of dosage is comparable.
  • Zandopa offers predictable efficacy and better tolerance compare to synthetic L-dopa, hence safe for long term use.
  • L-dopa of Zandopa is readily bioavailable, crosses BBB more easily than synthetic L-dopa, leading to better efficacy of the product.
  • Zandopa offers better patient compliance due to better toleranceand lesser side effects.

Zandopa Pharmacological Actions

  • Zandopa replenishes depleted stores of striatal dopamine in Parkinson's disease. Zandopa improves all the signs and symptoms of Parkinsonism. Bradykinesia responds first followed by rigidity and tremors.
  • Secondary motor symptoms such as disturbance in posture, gait, associated movements, facial expressions, speech, handwriting, swallowing and respiration are also prominently improved.
  • Improvement of these primary neurologiacal symptoms is accompanied by similar improvement in overall functional ability.
  • Zandopa Medicine also favourably influences the psychic behavioural pattern producing a sense of well being and an increased interest in self and surroundings.
Zandopa Safety: Long term safety studies conducted on laboratory animals have not shown any serious toxicity with Zandopa in a dose as high as 10% of the diet.

Zandopa Indications: Idiopathic Parkinsonism

Zandopa Composition (Each 7.5gm contains): Standardized processed seed powder of Kauncha
Mucuna Pruriens - 6.525gm in a flavoured base

Zandopa Precautions

  • All known precautions and contraindications as applicable to synthetic L-dopa formulations should also be followed while prescribing Zondopa.
  • Monoamine oxidase inhibitors, if taken by patients, must be discontinued atleast 2 weeks prior to institution of Zandopa.
  • As with levodopa, periodic evaluations of hepatic, heamatopoietic, cardiovascular and renal functions are recommended during extended trherapy with Zandopa.
  • Zandopa Medicine should be administered with caution in severe cadiovascular or plumonary disease, brochinal asthma, renal, hepatic or endocrine disease and in presence of peptic ulcer or chronic narrow angle glaucoma.

Zandopa Side Effects:

  • Zandopa Side Effects as encountered with synthetic L-dopa formulations have not been seen to the same severity with Zandopa.
  • Zandopa Side Effects include nausea, anorexia, cardiac irregularities, orthostatic hypotension, weight gain, hot flushes, numerous dyskinesias and psychiatric symptoms such as agitations, hallucinations, delusions and nightmares.
Suggestion for Parkinson's Disease Patient: Appropriate treatment helps to keep the patient working and enjoying active life for many years. With proper medication, patience, and perseverance to stay active, your sign and symptoms can be controlled for many years.

Zandopa Dosage: As directed by the physician.

Directions for use of Zandopa:
  • In a half glass of water (approx. 100ml) suspend prescribed dose of Zandopa Powder, stir and drink immediately. A measure of 7.5gm (approx.) is provided in the container.
  • L-dopa content of Zandopa powder is readily soluble in water. Patients finding difficulty in swallowing of the bulk may be advised to stir the powder in water for nearly one minute. Clear solution thus obtained may be consumed by the patient.
  • Not to be taken with milk.